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Table 4 Univariate and multivariate analyses of potential factors predicting high-flow nasal cannula success

From: ROX index versus HACOR scale in predicting success and failure of high-flow nasal cannula in the emergency department for patients with acute hypoxemic respiratory failure: a prospective observational study

Variable

Univariate OR (95% CI; p-value)

Multivariate OR (95% CI; p-value)

ROX at 1 h

1.41 (1.05–1.87; p = 0.020)

1.49 (1.09–2.05; p = 0.014)

ROX at 2 h

1.38 (1.07–1.79; p = 0.013)

1.43 (1.09–1.89; p = 0.010)

ROX at 6 h

1.27 (1.001–1.61; p = 0.049)

1.34 (1.02–1.76; p = 0.036)

HACOR at 1 h

0.81 (0.66–0.99; p = 0.043)

0.77 (0.62–0.96; p = 0.021)

HACOR at 2 h

0.83 (0.68–1.01; p = 0.066)

0.81 (0.66–0.99; p = 0.046)

HACOR at 6 h

0.83 (0.65–1.06; p = 0.132)

0.79 (0.61–1.03; p = 0.083)

Respiratory rate at 1 h

0.84 (0.75–0.91; p = 0.002)

0.84 (0.75–0.95; p = 0.004)

Respiratory rate at 2 h

0.81 (0.71–0.93; p = 0.002)

0.80 (0.68–0.93; p = 0.004)

Respiratory rate at 6 h

0.74 (0.62–0.89; p = 0.001)

0.74 (0.60–0.91; p = 0.004)

Pulse rate at 1 h

0.97 (0.94–0.99; p = 0.042)

0.97 (0.95–1.00; p = 0.075)

Pulse rate at 2 h

0.98 (0.95–1.00; p = 0.064)

0.98 (0.95–1.01; p = 0.100)

Pulse rate at 6 h

0.95 (0.91–0.98; p = 0.005)

0.95 (0.92–0.99; p = 0.021)

  1. The multivariate logistic regression models adjusted for age, sex, and underlying respiratory tract disease. Each multivariate model only employed one predictive score at one timepoint to avoid multicollinearity
  2. Abbreviations: OR Odds ratio, CI Confidence interval
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International Journal of Emergency Medicine

ISSN: 1865-1380

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