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Table 1 Comparison of the reported cases of anaphylactic shock induced by TXA among pediatrics with our case

From: Anaphylactic reaction to tranexamic acid infusion in a six-year-old child: a case report

Study

Ref. [17]

Ref. [19]

Ref. [6]

Our case

Agea

15

13

15

6

Age group

adolescence

adolescence

adolescence

childhood

Sex

male

male

female

female

Allergy history

-

asthma

asthma, hay fever

negative

TXA dosage

5 mgkg–1 bolus and 5 mgkg–1h–1

15 mgkg–1 bolus

1 g bolus

10 mgkg–1 bolus

SPTb

-

negative

negative

negative

IDTc

positive

positive

positive

positive

TXA concentration used for IDT

10 mgmL–1

-

10 mgmL–1

2 mgmL–1

Initial tryptase level

elevated

not elevated

-

-

  1. ayears
  2. bSkin prick test
  3. cIntradermal test