Prognostic significance of inferior vena cava volume defined by initial polytrauma CT-imaging: single-center experience of a level-1 trauma center

Table 5 Cox proportional hazard models of associations with 24-hour and 30-day mortality

Parameter	Univariable HR	95% CI	p value	Multivariable HR	95% CI	p-value
a). 24-hour mortality (n =32 patients)
Age	1.03	1.01 to 1.05	0.001	1	0.97 to 1.03	0.985
Sex (1=male)	0.82	0.37 to 1.84	0.637
BMI	0.99	0.9 to 1.09	0.845
ASA ≥III	5.95	2.83 to 12.05	<0.001	4.31	1.76 to 10.55	0.001
ISS	1.08	1.05 to 1.1	<0.001	1.05	1.02 to 1.07	<0.001
GCS ≤8 points	19.34	2.61 to 143.13	0.004	4.87	0.63 to 37.59	0.129
SBP ≤90 mmHg	12.19	5.11 to 29.09	<0.001	2.59	1 to 6.7	0.049
IVC volume, cm³	0.92	0.89 to 0.95	<0.001	0.96	0.93 to 0.99	0.025
b). 30-day mortality (n = 99 patients)
Sex (1=male)	1.01	0.64 to 1.58	0.973
BMI	1.05	1 to 1.1	0.035	1.04	0.99 to 1.1	0.12
ASA ≥III	3.01	2.01 to 4.51	<0.001	3.42	1.95 to 6.02	<0.001
ISS	1.07	1.05 to 1.08	<0.001	1.05	1.04 to 1.07	<0.001
GCS ≤8 points	8.23	3.82 to 17.73	<0.001	3.37	1.52 to 7.49	0.003
SBP ≤90 mmHg	5.35	3.6 to 7.96	<0.001	2	1.25 to 3.22	0.004
IVC volume, cm³	0.96	0.95 to 0.98	<0.001	0.99	0.98 to 1.01	0.219

HR hazard ratio, CI confidence interval, BMI body mass index, ASA American Society of Anesthesiologists classification, ISS injury severity score, GCS Glasgow coma scale, SBP systolic blood pressure, IVC inferior vena cava; bold numbers indicate statistical significance (p <0.05). Area under the receiver operating characteristic (AUROC) curve for 24-hour mortality a) 0.922 and for 30-day mortality b) 0.884.

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