Table 3 Summarize of Apelin-13
Aspect | Details |
|---|---|
Biomarker | Apelin-13 |
Type of Molecule | Peptide, a subtype of the Apelin family |
Role in TE disorders | Potential novel biomarker for the diagnosis of TE disorders, including DVT, PE, and stroke. |
Diagnostic Significance | are associated with endothelial function and cardiovascular health, making it a candidate for identifying TE conditions. |
Mechanism of Action | interacts with the APJ, influencing vascular tone, blood pressure, and endothelial cell proliferation. |
Current Research Status | Ongoing studies are exploring the utility of Apelin-13 in improving the sensitivity and specificity of TE diagnosis. |
Advantages over Existing Biomarkers | It may offer enhanced diagnostic accuracy in conjunction with existing biomarkers and clinical assessments. |
Challenges | Requires further validation in large-scale clinical trials to establish its diagnostic utility and standardize its measurement. |
Clinical Applications | Potential use in early diagnosis, risk stratification, and monitoring of TE disorders. |